The best Side of Promethazine With Codeine
The best Side of Promethazine With Codeine
Blog Article
We foresee reposting the pictures when we're able determine and filter out illustrations or photos that do not match the data supplied in the drug labels. NDC Codes
Nearly all of reports analyzing using promethazine in pregnancy didn't obtain an association with a heightened chance of congenital anomalies. In the handful of studies reporting an Affiliation, no regular pattern of malformations was mentioned.
The danger for serious breathing problems is increased when you start this medication, or if you take the wrong dose or choose far more of the medication than prescribed. Using this medication with Alcoholic beverages or other drugs that could potentially cause drowsiness or breathing difficulties may possibly trigger quite significant Uncomfortable side effects, such as Dying. Also, other medicines can have an impact on the removing of this product from the physique, which may have an effect on how it really works.
The usage of Promethazine with Codeine Oral Alternative in people with acute or critical bronchial asthma in an unmonitored placing or during the absence of resuscitative tools is contraindicated [seeCONTRAINDICATIONS (4)]. Opioid analgesics and antitussives, which include codeine, one of the Energetic components in Promethazine with Codeine Oral Remedy, really should not be Utilized in people with acute febrile disease associated with effective cough or in people with Persistent respiratory illness where interference with power to obvious the tracheobronchial tree of secretions would have a deleterious impact on the individual's respiratory functionality.
DailyMed will produce notification of updates and additions to Drug Label facts at this time revealed on this site by its RSS feed.
The consequences of concomitant use or discontinuation of cytochrome P450 3A4 inducers, 3A4 inhibitors, or 2D6 inhibitors with codeine are elaborate.
Promethazine hydrochloride wasn't mutagenic within the in vitro bacterial reverse mutation assay or clastogenic during the in vitro Chinese hamster ovary (CHO) cell chromosomal aberration assay.
This medication could cause you to additional sensitive into the Sunlight. Restrict your time and effort during the Solar. Keep away from tanning booths and sunlamps. Use sunscreen and wear protective outfits when outside. Convey to your medical professional straight away if you have sunburned or have pores and skin blisters/redness.
Promethazine with Codeine Oral Resolution need to be utilised with warning in patients with impairment of hepatic perform, and sufferers need to be monitored closely for respiratory depression, sedation, and hypotension.
You might have respiratory troubles or withdrawal symptoms if You begin or cease using specific other medicines. Inform your medical professional if In addition, you use specific antibiotics, antifungal medicines, seizure medication, or medicines to treat HIV or hepatitis C.
Codeine is altered into a strong opioid drug (morphine) in your body. In lots of people, this alteration comes about speedier and a lot more entirely than typical, which increases the hazard of incredibly critical Unintended effects.
In women with typical codeine metabolism (ordinary CYP2D6 exercise), the amount of codeine secreted into human milk is minimal and dose-dependent. There's no information on the consequences from the codeine on milk generation.
Codeine has minimal plasma protein binding with about 7 to twenty five% of codeine sure to plasma proteins. Codeine passes the blood Mind barrier as well as placental barrier. Little quantities of codeine and its metabolite, morphine, are transferred to human breast milk.
If you are get more info having any of those medication: Buprenorphine, butorphanol, nalbuphine, or pentazocine. Should you have been informed by your medical doctor that you are a swift metabolizer of some medication. Should you be breast-feeding. Will not breast-feed Whilst you consider promethazine and codeine. It's not an index of all medications or health problems that interact with promethazine and codeine. Tell your physician and pharmacist about your whole medications (prescription or OTC, normal products, vitamins) and health issues. You should Verify to make certain that it really is safe that you should consider promethazine and codeine with your entire medications and health issues. Tend not to start out, stop, or change the dose of any drug without checking with your health care provider. Connected/very similar drugs